What is Integrative structural Biology?

Integrative Structure Determination

collecting data from diverse sources at different levels of resolution,

translating data into spatial restraints

sampling by satisfaction of all the restraints to computationally generate an ensemble of structures

analyzing of the ensemble of solutions.

Goals & Perspectives

  • Integrate into one comprehensive picture of the structure, dynamics, and function of biomolecules
  • Provide key insights into development of new diagnostic and therapeutic tools
  • Perform sutiable structurally-informative experiemtns and develop computational methods to integrate diverse emerging sources of experimental data ranging from biophysical to genomic.


  • 64th Annual meeting of Biophysical Society, 2020. (김승중, 조영문, 한만혁)


Department of Physics,

KAIST (Korea Advanced Institute of Science and Technology), Korea E6-6 512

Phone: +82-42-350-2515 (Office)

+82-42-350-2555 (Lab)

e-mail: kim.sj@kaist.ac.kr